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Meridian Life Science Awarded SBIR by Centers for Disease Control and Prevention to Develop Rotavirus Vaccine

MEMPHIS, Tenn.--(BUSINESS WIRE)--Oct. 31, 2013-- Meridian Life Science, Inc., (MLS) of Memphis, Tennessee, a wholly-owned subsidiary of Meridian Bioscience, Inc. (NASDAQ:VIVO), has been selected by the Centers for Disease Control and Prevention (CDC) to develop a process for manufacture of a rotavirus vaccine. Funding for this activity will be provided through a Small Business Innovation Research (SBIR) contract. Process development will focus on optimization of growth and yield of the virus in cell culture, inactivation of the rotavirus harvest and, finally, purification of the virus prior to formulation and filling. This initial SBIR will fund research and development activities at Meridian Life Science which could lead to scale up and manufacture of a rotavirus vaccine for use in clinical trials. Meridian Life Science is a contract manufacturer offering production of vaccines and challenge stocks which employ current Good Manufacturing Practices (cGMP) as described in 21 CFR Parts 210 and 211.

According to the CDC’s website, rotavirus causes gastroenteritis (inflammation of the stomach and intestines). The rotavirus disease causes severe watery diarrhea, often with vomiting, fever, and abdominal pain. In babies and young children, it can lead to dehydration (loss of body fluids). Rotavirus is the leading cause of severe diarrhea in infants and young children worldwide. Globally, it causes more than a half a million deaths each year in children younger than 5 years of age.

Dr. Victor Van Cleave, Vice President of Research and Development (R&D) at Meridian Life Science said, “Meridian is pleased to have been selected by the CDC to receive this award. Rotavirus is a serious problem globally for infants and we feel honored to be a part of this program to assist in the eradication of this challenging health issue. This project was an excellent fit for Meridian’s core virology and virus based product manufacturing capabilities. We have previously partnered with scientists from the CDC to transfer in the methodologies for growth and propagation of this virus and will now collaborate with their scientists to ensure the successful and timely development of a rotavirus vaccine manufacturing process. Meridian and our scientists are proud to be a part of this development effort that could significantly impact the incidence and severity of rotavirus infections in children.”

Meridian is a fully integrated life science company that develops, manufactures, markets and distributes a broad range of innovative diagnostic test kits, purified reagents and related products and offers biopharmaceutical enabling technologies. Utilizing a variety of methods, these products and diagnostic tests provide accuracy, simplicity and speed in the early diagnosis and treatment of common medical conditions, such as gastrointestinal, viral and respiratory infections. Meridian’s diagnostic products are used outside of the human body and require little or no special equipment. The Company's products are designed to enhance patient well-being while reducing the total outcome costs of healthcare. Meridian has strong market positions in the areas of gastrointestinal and upper respiratory infections, serology, parasitology and fungal disease diagnosis. In addition, Meridian is a supplier of rare reagents, specialty biologicals and related technologies used by biopharmaceutical companies engaged in research for new drugs and vaccines. The Company markets its products and technologies to hospitals, reference laboratories, research centers, diagnostics manufacturers and biotech companies in more than 60 countries around the world. The Company’s shares are traded on NASDAQ’s Global Select Market, symbol VIVO. Meridian's website address is www.meridianbioscience.com.

Source: Meridian Bioscience, Inc.

Meridian Bioscience, Inc.
John A. Kraeutler, Chief Executive Officer, 513-271-3700